Kefir is fermented milk product as natural probiotics, has less acidic taste, yeasty aroma and foamed on stirred due to containing acid, alcohol and CO2 (Otles and Cagindi, 2003; Adriana and Socaciu, 2008). Raw material of kefir usually prepared from cow milk, but can also be prepared with other milk such as goat or sheep, coconut, rice and soy milk.
According to Bergmann et al., the kinds of microorganism in kefir depend on origin of kefir grain that existing in polysaccharides matrix, where in the fermentation process will produce a variety of substances such amine, vitamins, acids, ethanol, and volatile compounds.
Kefir grains are added in kefir fermentation process which makes a difference in comparison to yoghurt fermentation. Diameter of kefir grains ranges from 0.3-3.5 cm, and the grains consisted of 89-90% water, 0.2% lipids, 3% proteins, 6% sugars and 0.7% ashes. In addition, traditionally, yogurt has only one or two bacteria, whereas kefir tends to have several probiotic bacteria.
Various type of microorganism that present in kefir grains are lactic acid and acetic acid bacteria, yeasts and fungi. Several organic acids resulted from fermentation by probiotics such as Lactobacillus kefiranofaciens, Candida kefir, Saccharomyces boluradii and resulted during storage can a role as an inhibitory substances which will affect their ability to survive.
The mechanisms of inhibitory effect of these organic acids through the toxicity due to membrane cells damage, cytosol acidification and anion accumulation intracellularly. For their importance of physiological requirements, the lactic acid bacteria (LAB) has regulatory activity which maintain their pH in cytoplasms and inracellular.
Prebiotics are non-digestible carbohydrate that resist to enzymatic degradation in saliva and small intestinal, so that it can be used as a substrat and stimulate a specific bacteria in the host colon. Inulin-type prebiotics are linear fructans, have a minimum two and maximum 60 fructose units with beta fructosyl-fructose glycosidic, starting with glucose or no glucose unit, or with low or higher glucose proportion.
Inulin can be hydrolyzed by some strains of yeast that have inulinase activity, as determined previously by Cruz-Guerrero et al., that two strains Kluyveromyces marxianus and also one strain of K. lactis var. lactis showed very good inulinase producers. Information of inulin addition in fermented milk as an antioxidant and the changes in its antioxidant during storage is still limited.
Phenolic compounds (phenolic acids, flavonoids, anthocyanins and proanthocyanidins), tocopherols and tocotrienols (vitamin E), γ-oryzanol, and phytic acid are antioxidant components in rice. The antioxidant phenolic that present in plants have benefecial effects on clotting of blood and tumorogenesis.
Goat milk is rich in various physiologically functional components, including proteins, vitamins (such as vitamins E and C), flavonoids, and carotenoids with antioxidant properties. The antioxidant activity of goat milk is significantly affected by pasteurization treatment, milk lactation stages, type of feeding and geographic location.
Lifestyle changes including dietary habit can cause the various degenerative diseases such as diabetes mellitus (DM), which tend to increase from year to year. Various antidiabetic drugs have been widely used for a long time such as glibenclamide having a hypoglycemic effect. The treatment of DM may not utilize antidiabetic drugs, as has been observed previously that use plant/herbal components and utilize animal products such as fermented milk.
The profile of β- cells on the islets of Langerhans pancreatic tissue of diabetic rats treated with virgin coconut oil (VCO), and Nigella sativa L. (an annual herbaceous plant) has been studied by Uray and Kanter et al., respectively. While, the effect of fermented water kefir product on glycemic status and antioxidative properties of STZ-induced hyperglycemia has been studied by Judiono et al..
The purpose of this study was to evaluate the properties of goat milk kefir by 50% substitution with black rice extract, and its influence on the improvement of β-cells in pancreatic tissue of STZ-NA induced diabetic rats. That and other natural meds (viagra oral jelly, kamagra oral jelly) watch on Canadian Health Care Store: http://www.canadianhealthmall.com.